Morphogenesis of Arteriosclerosis

Experimental Arteriosclerosis

Arteriosclerotic lesions have been produced in monkeys (Macaca nemestrina) by selective removal of the vascular endothelium with an intra-arterial balloon catheter. Immediately after de-endothelialization a platelet layer covers the denuded area. This thrombus is gradually removed and by 7 days the vessel appears to be largely reendothelialized. Beginning at day 4, smooth muscle cells undergo m...

Spontaneous Arteriosclerosis in Rabbits

Cerebral arteriosclerosis.

The Biology of Arteriosclerosis

The experimental approach to the study of arteriosclerosis has yielded disappointing results in comparison to the vast effort expended upon the problem. Any new method of attack excites interest, and it is the special virtue of this monograph to have placed in evidence, with great clarity and a profusion of beautiful illustrations, the existence of a rich intramural vascular plexus, which has a...

Arteriosclerosis in Parkinsonism.

Some textbooks on general and neurological medicine give the impression that cerebral arteriosclerosis is an important cause of Parkinsonism (e.g., Alpers, 1945; Yater, 1949; Purves-Stewart and Worster-Drought, 1952; Wilson, 1955; Cecil and Loeb, 1959; Grinker, Bucy, and Sahs, 1959; Merritt, 1959; Baker, 1962; Brain, 1962). Whether or not this is so, it is often very difficult to distinguish cl...